Type 2 diabetes mellitus (T2DM) is preceded by a modifiable period of prediabetes, creating opportunities for scalable prevention through digital health interventions (DHIs). This scoping review mapped intervention types, study characteristics, outcomes, methodological limitations, and research gaps in DHIs for preventing T2DM among at-risk adults. Following Arksey and O’Malley’s framework, Joanna Briggs Institute guidance, and PRISMA-ScR, 52 records were identified through structured searches and citation tracking. After removing 16 duplicates, 36 records were screened using Population–Concept–Context criteria, yielding 13 eligible studies or trial protocols. The interventions comprised mobile application-based diabetes prevention programs, SMS/text messaging, telehealth or telecoaching, wearables and glucose monitoring, artificial intelligence-enabled coaching, and multicomponent hybrid platforms. Commonly assessed outcomes included weight, body mass index, HbA1c, fasting glucose, incident T2DM, behavioral change, and program engagement. Overall, DHIs showed short- to medium-term benefits for weight reduction and glycemic risk markers, while several landmark trials reported reductions in T2DM incidence. However, the evidence was constrained by short follow-up periods, small and homogeneous samples, high attrition, self-reported outcomes, and limited economic evaluation. No eligible Indonesian prevention study was identified. Future research should prioritize long-term, implementation-informed comparative effectiveness trials in underrepresented Southeast Asian populations, particularly Indonesia, while evaluating sustainability, scalability, equity, and cost-effectiveness.
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