Highlights: Ceftriaxone and Cefazolin were the most used antibiotics. The most common inappropriate prescribing practices were incorrect dosing intervals and antibiotic use without clear clinical indications. Abstract Introduction: Inappropriate use of antibiotics can cause adverse side effects, such as the emergence of antibiotic resistance. The use of antibiotics without clear indications is common in surgical cases. Currently, data on the quality of antibiotic use in surgical cases remain widely unavailable. Methods: This study was a descriptive retrospective study using 136 medical records in the Inpatient Room at Universitas Airlangga Hospital, Surabaya, Indonesia. The subjects of this study were low-care surgical patients at Universitas Airlangga Hospital, Surabaya, Indonesia. The study variables included antibiotic use, length of hospital stay, sex, age, and type of surgery, and the data were entered into a Microsoft Excel spreadsheet to generate frequency distribution tables. Results: The quality of appropriate and rational antibiotic use (category 0) was 62.33%, inappropriate antibiotic use (category I) was 0.9%, inappropriate antibiotic use in terms of dose/interval/route of administration (category II) was 21.5%, inappropriate antibiotic use in terms of efficacy/some were less toxic/some were cheaper/some had a narrower spectrum (category IV) was 0.9%, antibiotic use without indication (category V) was 10.76%, and category VI was 2.2%. Conclusion: Antibiotic prescribing among low-care surgical patients at Universitas Airlangga Hospital, Surabaya, Indonesia, showed a moderate level of appropriateness according to the Gyssens criteria.
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