Although the Maternal and Child Health (KIA) Handbook is widely promoted in Indonesia to support maternal knowledge, child growth monitoring, and stunting prevention, evidence comparing predisposing factors influencing its utilization between urban and rural settings remains limited. This study aimed to determine the relationship between maternal predisposing factors and KIA Handbook utilization in urban and rural areas of South Sulawesi Province. A quantitative analytical observational study with a cross-sectional design was conducted from January to February 2025 among 126 mothers in the urban catchment area of Kassi Kassi Community Health Center, Makassar City, and 113 mothers in the rural catchment area of Bontoa Community Health Center, Maros Regency. Respondents were selected using purposive sampling, and data were analyzed using univariate and bivariate analyses. KIA Handbook utilization was higher in rural than in urban areas. In urban areas, attitude (p<0.001) and age (p=0.031) were significantly associated with handbook utilization, whereas knowledge (p=0.066) and education (p=0.215) were not. In rural areas, knowledge (p<0.001), attitude (p<0.001), and age (p=0.044) were significantly associated with utilization, while education was not (p=0.091). These findings support context-specific maternal health interventions that strengthen knowledge in rural communities and promote positive attitudes toward KIA Handbook utilization across both settings.
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