Kemampuan Fotoproteksi Minyak Biji Raspberry dan Cellulose Nanocrystal

Tiara Tri Andini (Prodi Farmasi, Fakultas Farmasi dan Sains, Universitas Islam Bandung, Indonesia)
Arlina Prima Putri (Prodi Farmasi, Fakultas Farmasi dan Sains, Universitas Islam Bandung, Indonesia)
Budi Prabowo Soewondo (Prodi Farmasi, Fakultas Farmasi dan Sains, Universitas Islam Bandung, Indonesia)

Bandung Conference Series: Pharmacy
579 - 586

Abstract. Excessive exposure to ultraviolet (UV) rays can cause various skin disorders, thereby driving the development of natural-ingredient-based sunscreens as a safer alternative. This literature review aims to analyzed the photoprotective potential of raspberry seed oil (Rubus idaeus L.), examine the characteristics and functions of cellulose nanocrystals (CNC), and evaluate the potential synergy between these two ingredients in sunscreen formulations. The study was conducted using a narrative literature review method, with data sources consisting of scientific articles obtained from PubMed, ScienceDirect, Scopus, and Google Scholar. The literature was selected based on its relevance to the research topic and then analyzed descriptively through the synthesis and comparison of previous research findings. The results of the study indicate that raspberry seed oil contains various bioactive compounds, such as unsaturated fatty acids, tocopherols, phytosterols, carotenoids, and phenolic compounds, which contribute to antioxidant activity and have the potential to provide photoprotective effects. On the other hand, CNC acts as a Pickering stabilizer capable of enhancing emulsion stability by inhibiting droplet coalescence and maintaining a homogeneous distribution of active ingredient. Based on the study’s findings, the combination of raspberry seed oil and CNC shows promise for the development of more stable and effective natural-ingredient-based sunscreen formulations, although scientific evidence regarding the integration of these two ingredients remains relatively limited. Abstrak. Paparan sinar ultraviolet (UV) secara berlebihan dapat menyebabkan berbagai gangguan pada kulit, sehingga mendorong pengembangan tabir surya berbasis bahan alam sebagai alternatif yang lebih aman. Studi literatur ini bertujuan untuk menganalisis potensi fotoproteksi minyak biji raspberry (Rubus idaeus L.), mengkaji karakteristik dan fungsi Cellulose Nanocrystal (CNC), serta mengevaluasi potensi sinergi kedua bahan tersebut dalam formulasi tabir surya. Kajian dilakukan menggunakan metode narrative literature review dengan sumber data berupa artikel ilmiah yang diperoleh dari PubMed, ScienceDirect, Scopus, dan Google Scholar. Literatur dipilih berdasarkan kesesuaian dengan topik penelitian, kemudian dianalisis secara deskriptif melalui proses sintesis dan perbandingan hasil penelitian terdahulu. Hasil kajian menunjukkan bahwa minyak biji raspberry mengandung berbagai senyawa bioaktif, seperti asam lemak tak jenuh, tokoferol, fitosterol, karotenoid, dan senyawa fenolik yang berkontribusi terhadap aktivitas antioksidan dan berpotensi memberikan efek fotoproteksi. Di sisi lain, CNC berperan sebagai pickering stabilizer yang mampu meningkatkan stabilitas emulsi dengan menghambat koalesensi droplet serta menjaga distribusi bahan aktif tetap homogen. Berdasarkan hasil kajian, kombinasi minyak biji raspberry dan CNC memiliki prospek yang menjanjikan dalam pengembangan formulasi tabir surya berbasis bahan alam yang lebih stabil dan efektif, meskipun bukti ilmiah mengenai integrasi kedua bahan tersebut masih relatif terbatas.