<![CDATA[Abstract. Moringa leaves (Moringa oleifera L.) contain bioactive compounds with potential as antioxidants, making them suitable for development into a face mist. This study aimed to formulate a face mist preparation from the ethyl acetate fraction of moringa leaves that meets quality evaluation requirements, as well as to determine its antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The research was conducted through the preparation of simplicia, standardization of simplicia, extraction using the maceration method with 96% ethanol, fractionation via liquid-liquid extraction, formulation of face mist with ethyl acetate fraction concentrations of 0,1%(F1), 0,5%(F2), 1%(F3), quality evaluation of the preparations including organoleptic testing. homogeneity, pH, spray spreadability, and specific gravity, as well as antioxidant testing using the DPPH method with vitamin C as a comparator. The results showed that all formulas met the quality requirements for the preparation. The IC50 value of vitamin C was 4.08 ppm, while F1, F2, and F3 had IC50 values of 92,146 ppm; 80,4515 ppm; and 66,4109 ppm, respectively. All three formulas exhibited strong antioxidant activity, with F3 showing the highest antioxidant activity due to its lowest IC50 value. Based on the results, it can be concluded that the face mist formulated from the ethyl acetate fraction of moringa leaves was successfully developed, met the quality requirements for the preparation, and possessed strong antioxidant activity. Abstrak. Daun Kelor (Moringa oleifera Lam.) mengandung senyawa bioaktif yang berpotensi sebagai antioksidan sehingga dapat dikembangkan menjadi face mist. Penelitian ini bertujuan untuk memformulasikan sediaan face mist fraksi etil asetat daun kelor yang memenuhi persyaratan evaluasi mutu serta mengetahui aktivitas antioksidannya menggunakan metode 2,2-difenil-1-pikrilhidrazil (DPPH).Penelitian dilakukan melalui pembuatan simplisia, standarisasi simplisia, ekstraksi dengan metode maserasi menggunakan etanol 96%, fraksinasi secara ekstraksi cair-cair, formulasi face mist dengan konsentrasi fraksi etil asetat 0,1% (F1), 0,5% (F2), dan 1% (F3), evaluasi mutu sediaan yang meliputi uji organoleptis, homogenitas, pH, daya sebar senprot, dan bobot jenis serta pengujian antioksidan menggunakan metode DPPH dengan vitamin C sebagai pembanding. Hasil penelitian menunjukan bahwa seluruh formula memenuhi persyaratan mutu sediaan. Nilai IC50 Vitamin C sebesar 4,08 ppm, sedangkan F1, F2 dan F3 berturut turut sebesar 92,146 ppm; 80,4515 ppm; dan 66,4109 ppm. Ketiga formula memiliki aktivitas antioksidan kategori kuat, dengan F3 menunjukan aktivitas antioksidan paling tinggi karena memiliki nilai IC50 paling rendah. Berdasarkan hasil penelitian dapat disimpulkan bahwa face mist fraksi etil asetat daun kelor berhasil diformulasikan, memenuhi persyaratan mutu sediaan, dan memiliki aktivitas antioksidan yang kuat.]]>
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