Hyperbaric Oxygen Therapy (HBOT) is a medical intervention that involves administering pure oxygen at high pressure for various conditions like decompression sickness, severe anemia and including carbon monoxide (CO) poisoning. This literature review aims to evaluate the effectiveness of HBOT in reducing neurocognitive symptoms caused by CO poisoning, as well as to review the mechanisms, indications, contraindications, and application of Hyperbaric Oxygen Therapy in Carbon Monoxide Poisoning. The review findings indicate that HBOT significantly enhances tissue oxygenation and accelerates the healing process, which can reduce the risk of neurocognitive damage. Hyperbaric Oxygen Therapy has also been found to modulate inflammatory responses, which play a crucial role in the recovery of patients with CO poisoning. However, some studies show variations in the long-term effectiveness of HBOT on neurocognitive symptoms, highlighting the need for further research. This literature review concludes that HBOT offers significant benefits in the treatment of CO poisoning; however, further research is needed to optimize clinical use and ensure its long-term effectiveness.
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