<![CDATA[Chronic kidney disease (CKD) is a progressive disorder characterized by a gradual decline in kidney function, resulting in the accumulation of metabolic waste products, including serum creatinine. Serum creatinine is one of the most commonly used laboratory parameters for assessing renal function. Physiologically, sex influences serum creatinine levels because of differences in muscle mass; however, findings regarding this association among patients with CKD remain inconsistent. This study aimed to analyze the association between serum creatinine levels and sex among patients with chronic kidney disease at Hadji Boejasin Regional General Hospital. This study employed a descriptive analytic design with a cross-sectional approach. A total of 59 patients diagnosed with chronic kidney disease were included using the total sampling technique based on medical record data. Descriptive statistics were used to summarize participant characteristics. The association between variables was analyzed using the Mann–Whitney U test because the serum creatinine data were not normally distributed according to the Shapiro–Wilk test. Of the 59 participants, 31 (52.5%) were female and 28 (47.5%) were male. The overall mean serum creatinine level was 9.25 ± 6.30 mg/dL. Female patients had a slightly higher mean serum creatinine level (9.55 mg/dL) than male patients (8.91 mg/dL). However, the difference was not statistically significant (p = 0.434). There was no statistically significant association between sex and serum creatinine levels among patients with chronic kidney disease at Hadji Boejasin Regional General Hospital. The findings suggest that serum creatinine levels in CKD patients are more strongly influenced by the degree of renal function impairment than by biological differences between males and females]]>
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