<![CDATA[The rapid adoption of Artificial Intelligence (AI)-enabled Intelligent Decision Support Systems (IDSS) has transformed decision-making across multiple sectors. However, increasing AI complexity often limits users’ understanding of recommendation processes, creating challenges for responsible human-AI interaction. Existing studies mainly emphasize explainability and transparency from technical perspectives while providing limited evidence regarding their influence on responsible interaction and decision quality. This study investigates the effects of Perceived Explainability and Perceived Transparency on Responsible Human-AI Interaction and Decision Quality, including the mediating role of Responsible Human-AI Interaction. Grounded in the Human-AI Teaming perspective and the Responsible AI Framework, this quantitative study employs a survey of 180 respondents with experience using AI-enabled Intelligent Decision Support Systems. Data will be analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM). The study is expected to demonstrate that explainability and transparency strengthen responsible human-AI interaction, which subsequently enhances decision quality. These findings are expected to enrich responsible AI literature and provide practical guidance for designing transparent, human-centered Intelligent Decision Support Systems that promote trustworthy decision-making and reinforce the humanistic values underpinning intelligent technologies]]>
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