<![CDATA[Background: Hypertension affects not only physical health but also quality of life, depression, and anxiety. Digital-based psychospiritual interventions may serve as a supportive strategy in hypertension management to address these psychosocial impacts. Objective: This systematic review evaluated the effectiveness of digital-based psychospiritual interventions on quality of life, depression, and anxiety among individuals with hypertension. Methods: The review followed PRISMA 2020 guidelines. Literature searches were conducted in PubMed, EBSCO, Scopus, Oxford Journal, and ProQuest for studies published between 2021 and 2026. Eligible studies were selected based on predefined inclusion and exclusion criteria and critically appraised using the Joanna Briggs Institute (JBI) Critical Appraisal Tool. Eight studies were included, and findings are presented according to intervention characteristics and reported outcomes. Result: Digital-based psychospiritual interventions demonstrated potential benefits for psychosocial outcomes, including improvements in quality of life, depression, and anxiety. However, the magnitude and consistency of these effects varied depending on intervention characteristics, study design, and population. These benefits were associated with enhanced emotion regulation, stress management, self-awareness, and patient engagement in care. Conclusion: Digital-based psychospiritual interventions may be considered a supportive nonpharmacological approach in hypertension management. Further research employing more rigorous designs and standardized outcome measures is warranted.]]>
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