JOURNAL LA MEDIHEALTICO
Vol. 7 No. 4 (2026): Journal La Medihealtico

Relationship Between Hypertension History and Nutritional Status with the Incidence of Preeclampsia in Pregnant Women: Literature Review

Arifah Ayu Tri Wahyuni (Medical Profession Study Program, Faculty of Medicine, Universitas Muslim Indonesia)
Susiawaty Mustafa Syarief (Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Muslim Indonesia)
Muhammad Jabal Nur (Department of Internal Medicine, Faculty of Medicine, Universitas Muslim Indonesia)
Nurhikmawati Nurhikmawati (Department of Cardiology, Faculty of Medicine, Universitas Muslim Indonesia)
Akina Maulidhany Tahir (Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Muslim Indonesia)



Article Info

Publish Date
07 Sep 2026

Abstract

Preeclampsia is one of the leading causes of perinatal morbidity and mortality worldwide, particularly in developing countries. High intake of saturated fats, pro-inflammatory diets, and excess body weight increase the risk of hypertension during pregnancy. A history of hypertension and maternal nutritional status are recognized as important risk factors contributing to the occurrence of preeclampsia. This literature review aimed to determine the relationship between a history of hypertension and nutritional status with the incidence of preeclampsia in pregnant women, based on several sources obtained through the internet, including research findings from international and national journals, citations from the Faculty of Medicine UMI, ClinicalKey, textbooks, and conference proceedings published between 2015 and 2026. The review findings indicate that the majority of studies reported that a history of hypertension significantly increases the risk of preeclampsia. In addition, excessive nutritional status such as overweight and obesity is strongly associated with a higher incidence of preeclampsia through mechanisms involving chronic inflammation, insulin resistance, oxidative stress, and endothelial dysfunction. Conversely, undernutrition and deficiencies of certain micronutrients may worsen the risk through impaired placental perfusion. The combination of a history of hypertension and suboptimal nutritional status exerts a synergistic effect on increasing the risk of preeclampsia. It is concluded that a history of hypertension and nutritional status are important determinants of preeclampsia; therefore, preconception screening, blood pressure control, and nutritional interventions need to be strengthened as preventive strategies.

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Journal Info

Abbrev

JournalLaMedihealtico

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Journal La Medihealtico is peer reviewed, open access Academic and Research Journal which publishes Original Research Articles, Review Article, Case Report editorial comments etc. in all fields of medical sciences and health sciences including Health Care Delivery, Health Care Research, ...