Poor psychological well-being is an important issue that must be addressed in managing Diabetes millitus. Uncertainty of diabetes mellitus indicates the inability of individuals to determine the meaning of events associated with a disease. The uncertainty of diabetes mellitus causes stress because of the uncertainty in the disease process. The purpose of this study was to determine the description of Uncertainty in illness and psychological status in Diabetes mellitus clients in the Jember Health Center Area. The design of this study was explanatory survey with cross sectional approach. The study population was all Diabetes millitus clients in the Jember Community Health Center. The sample size of 250 Diabetes millitus clients was recruited by simple random sampling technique. The data used in this research is descriptive statistical analysis so that the results will be obtained in the form of a frequency distribution. The results showed that the highest level of client expectations was with a low expectation rate of 51.2%. The highest level of distress of respondents who had Diabetes millitus was in the category of distress by 50.4%. The level of anxiety felt by most respondents was in the category of disturbance by 47.6% and uncertainty was in the less category by 63.2%. A greater understanding of the nature of uncertainty and psychological status in this context may not only provide a unique picture and challenge of Diabates mellitus clients, but also illustrate how future interactions between health care providers, education programs, and interventions will be increased in Diabetes millitus clients
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