The mental health crisis of students in the contemporary era demands a comprehensive approach that integrates spiritual, emotional, and mental dimensions in a balanced manner. This study aims to develop a conceptual framework for holistic education based on the Qur’an to address the mental health problems of the younger generation. Using a literature study method with a qualitative descriptive-analytical approach, this study analyzed literature sources including the Qur’an, commentaries, indexed scientific journals, and reference books related to Islamic psychology and holistic education. The results revealed that the Qur’an provides a comprehensive psychological framework that includes the development of spiritual awareness (taqwa, tawakkal, dhikr), emotional intelligence (sabr, syukr, emotional regulation), and mental-cognitive health (cognitive reframing, resilience, tafakkur) integrated within the paradigm of tauhid. These three dimensions form a dynamic, mutually reinforcing system, with spirituality as a meta-framework that provides meaning, emotional intelligence as a mediator of values-behaviors, and mental health as a cognitive capacity that produces a synergistic effect. The implementation of holistic education requires curriculum transformation through an infusion approach, student-centered pedagogy, a spiritually caring school culture, and teacher competency as holistic mentors. Quranic spiritual practices have been shown to have therapeutic effects through neurobiological and psychological mechanisms that create peace of mind and resilience. Longitudinal research confirms that transformation is sustainable because the internalization of values forms a sustainable identity and worldview. The Quran-based holistic education model offers an effective, contextually relevant, and transformative solution to address students’ mental health crisis while achieving the national education goal of developing Indonesians who are faithful, have noble character, and are holistically healthy.
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