Clean and healthy living behavior remains a critical determinant of student wellbeing, yet the information environment in which today's university students form health habits has changed dramatically. This narrative review synthesizes 25 peer-reviewed studies to examine how health knowledge, chiefly measured as e-health literacy, and social media use jointly shape clean and healthy living behavior among university students. Following a PRISMA-informed search and screening process across Google Scholar, PubMed, DOAJ, and Scopus-indexed sources, the review integrates international e-health literacy research with Indonesia's Perilaku Hidup Bersih dan Sehat (PHBS) tradition, two literatures that have rarely been read together. Findings show that higher e-health literacy and disease-specific knowledge consistently and directly predict stronger health-promoting behavior across diverse national contexts. Social media use for health purposes similarly correlates with improved handwashing, dietary, and physical-activity outcomes, particularly on visual platforms such as Instagram and TikTok, but problematic or excessive use is associated with sedentary behavior, disrupted sleep, and greater exposure to misinformation. E-health literacy and risk perception function as mediators and moderators that determine whether social media exposure converts into durable behavior change, while peer influence and health beliefs often outweigh social media exposure on its own. The review proposes an integrated conceptual model in which knowledge acts both directly on behavior and as a literacy filter on social media's effect, and recommends that campus health promotion combine literacy-building curricula with credible, platform-specific content strategies.
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