<![CDATA[The aim of this research was to know the difference of ethanol extract and extract of ethyl acetate of pepper leaf (Piper nigrum L) to antimicrobial activity of Staphylococcua aureus, Escherichia coli and Candida albicans. The maceration method has been used to extract the pepper leaf by using two solvents ie 70% ethanol and ethyl acetate. The extract results were then tested for antimicrobial activity. The result of pepper ethanol extract obtainedby the higher yield was 24,64% compared with ethyl acetate extract 9,18%. Leaf pepper ethanol extract had higher antimicrobial activity than pepper acetate leaves extract against Staphylococcua aureus, and Escherichia coli but did not inhibit Candida albicans fungi at concentration of 10%]]>
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