<![CDATA[Hypertension remains a major global health problem requiring effective management. This quasi-experimental study examined whether acupressure reduces blood pressure among hypertensive patients receiving primary healthcare. Using a pre-test post-test non-randomized control group design, 40 hypertensive patients (45–60 years) at Puskesmas Kaliwungu Kudus, Indonesia, were assigned via purposive sampling to an intervention group (acupressure at LI4, LV3, GB20, and ST36 for seven days; n = 20) or a control group (standard care; n = 20). Data were analyzed using Wilcoxon, Mann–Whitney, and ANCOVA tests. The intervention group showed greater reductions in systolic (27.50 ± 7.70 vs 5.75 ± 7.83 mmHg) and diastolic blood pressure (17.00 ± 6.37 vs 5.00 ± 7.07 mmHg) than controls (all p = 0.008), with very large effect sizes (Cohen’s d = 2.36 and 1.55). ANCOVA confirmed the group effect remained significant after adjusting for age, gender, BMI, adherence, and comorbidity (both p = 0.001). Acupressure significantly reduced blood pressure and may serve as a practical complementary therapy in primary healthcare.]]>
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