The selection of donors based on smoking habits is an important process to ensure the availability of safe, high-quality blood. This study aims to analyze the correlation between smoking habits and blood hemoglobin levels in men at the Indonesian Red Cross Blood Transfusion Unit in Balikpapan. An analytical observational study with a cross-sectional design was conducted involving 99 male donors who were purposively selected based on their smoking intensity. Hemoglobin levels were measured using a standard hematology analyzer, while smoking habits were evaluated through structured interviews. Data were analyzed using Pearson's correlation test to evaluate the relationship between smoking categories and hemoglobin levels. The results showed a significant positive correlation, with higher smoking intensity associated with increased hemoglobin concentration. These findings confirm the physiological mechanism of compensatory erythropoiesis in smokers and highlight the importance of considering lifestyle factors during donor selection. This study provides insight into the hematological effects of smoking in clinical practice.
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