Green Medical Journal
Vol 6 No 1 (2024): Green Medical Journal

Effect of Dangke on Changes in Neutrophil to Lymphocyte Ratio in Obese White Rats

Alya Muthia Nur Amari Natsar (Student of the Medical Education Study Program, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia)
Asrini Safitri (Department of Nutrition Clinic, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia)
Rezky Pratiwi L Basri (Department of Histology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia)
Sri Julyani (Department of Pathology Clinic, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia)
Irna Diyana Kartika (Department of Pathology Clinic, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, Indonesia)



Article Info

Publish Date
04 Jun 2024

Abstract

Introduction: Obesity is associated with inflammation. Previous research has found that obesity determined by Body Mass Index (BMI) and Waist Circumference (LP) is associated with inflammation. Dangke contains Indigenos Lactic Acid Bacteria. The presence of lactic acid bacteria in fermented products has very positive benefits for health. The function of papaya sap which is used in making dangke, can act as an antibacterial and anti-inflammatory ingredient. Methods: Pure experimental research with a design, namely Pre-Post Randomized Clinical Trial Design. Data analysis used the independent T-test/Mann-Whitney test with a value <0.05. Results: The difference in the mean levels of Neutrophil to Lymphocyte (NLR) in the Intervention and control groups obtained a p-value of 0.94 which means that there is no relationship between control and intervention on NLR levels. The average change in NLR levels in the control group p-value of 0.61 which means there is no significant change in NLR levels in test 1 and test 2. The average change in NLR levels in the intervention group before and after the intervention was given a p-value of 0.07, which means there was no significant change in NLR levels in the intervention group. Conclusion: This study showed that intervention with Dangke did not yield a significant alteration in the NLR levels within the animal model of obesity.

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Journal Info

Abbrev

gmj

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Green Medical Journal (GMJ) is a peer-reviewed, open-access journal that publishes original research articles, review articles, and interesting case reports. The journal focuses on promoting medical and health sciences, derived from basic sciences, clinical and community health research, both in ...