Hypertension remains a leading global risk factor for cardiovascular mortality. While lifelong pharmacological therapy is essential, poor medication adherence is a critical challenge. This study aimed to evaluate the association between familial support and medication adherence among hypertensive patients through a comparative analysis at X Hospital and Y Hospital. Using a quantitative cross-sectional design, 350 respondents were recruited via purposive sampling. Data were collected utilizing a validated Family Support Questionnaire and the Probabilistic Medication Adherence Scale (ProMAS). Descriptive analysis showed a high prevalence of familial support at both X Hospital (85.3%) and Y Hospital (87.0%). However, Chi-square tests revealed a significant difference in medication adherence levels ($p 0.001$), with Y Hospital reporting a higher proportion of "High Adherence" (84.5%) compared to X Hospital (33.3%). Despite this baseline difference, Spearman’s rank correlation demonstrated a significant positive relationship between familial support and adherence at both X Hospital ($r = 0.250$, $p = 0.004$) and Y Hospital ($r = 0.317$, $p 0.001$). The primary limitations of this study are its cross-sectional design and reliance on purposive sampling, which restrict causal inferences. In conclusion, stronger family engagement is significantly associated with better medication adherence across different healthcare settings.
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