<![CDATA[Tuberculosis remains a major infectious disease that threatens child health, particularly in communities where parental knowledge of transmission and prevention is still limited. This study aimed to determine the effect of health education on parental knowledge regarding the prevention of tuberculosis in children at Kenali Besar Community Health Center, Jambi City. This research used a quantitative approach with a pre-experimental one-group pre-test and post-test design. The population consisted of 753 parents visiting the immunization room, and 34 respondents were selected using purposive sampling. Data were collected through a knowledge questionnaire before and after the health education intervention and analyzed using univariate and bivariate analysis with a T-test. The results showed that the mean parental knowledge score increased from 6.38 before the intervention to 8.15 after the intervention. The statistical test obtained a p-value of 0.001, indicating a significant effect of health education on parental knowledge. These findings suggest that structured health education can improve parents’ understanding of tuberculosis transmission, cough etiquette, environmental hygiene, and early prevention. The study implies that community health centers should integrate routine tuberculosis education into child health services, Posyandu activities, and other community-based health promotion programs.]]>
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