<![CDATA[Scabies is a highly contagious skin disease caused by infestation of the mite Sarcoptes scabiei and remains prevalent in densely populated settings such as Islamic boarding schools (pesantren). Knowledge is considered an important factor in shaping positive attitudes and preventive behavior toward scabies among students (santri), yet empirical findings on this relationship remain inconsistent across studies. This study aimed to examine the relationship between knowledge and both attitudes and preventive behavior toward scabies among female santri at Madrasah Aliyah, Daarul Muttaqien 1 Modern Islamic Boarding School. A quantitative descriptive-correlational design with a cross-sectional approach was used, involving 85 respondents selected through total sampling. Data were collected using structured questionnaires and analyzed with the Chi-Square test. The results showed that most respondents had good knowledge (67.1%), good attitudes (76.5%), and good preventive behavior (58.8%). Chi-Square analysis revealed significant associations between knowledge and attitudes (p = 0.000) and between knowledge and preventive behavior (p = 0.000). These findings indicate that knowledge plays an important, though not exclusive, role in shaping attitudes and behavior, since positive attitudes and behavior can also develop through non-cognitive pathways such as parental upbringing, peer modeling by senior students, and supervision by pesantren caregivers. Health education programs on scabies prevention should therefore combine knowledge enhancement with peer-based role modeling and stronger social support within the pesantren environment.]]>
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