<![CDATA[Hypertension remains a major global health concern and a leading risk factor for cardiovascular disease. Non-pharmacological interventions play an important role in nursing practice to support blood pressure control. Isometric handgrip exercise has been reported to reduce blood pressure; however, evidence from inpatient clinical settings remains limited. To examine the effect of isometric handgrip exercise on blood pressure in hypertensive patients using a case study approach. A descriptive case study was conducted involving four hypertensive patients admitted to Kultura Ward, 6th Floor, RS UNS. The intervention consisted of isometric handgrip contractions performed for approximately 12 minutes in a single session. Blood pressure was measured before and five minutes after the intervention. Data were analyzed descriptively by comparing pre- and post-intervention values. All patients demonstrated a reduction in systolic blood pressure, with a mean decrease of 13.25 mmHg (range 12–16 mmHg). Diastolic changes varied; three patients experienced reductions of 2–5 mmHg, while one patient showed a 6 mmHg increase. Isometric handgrip exercise shows potential as a simple and applicable non-pharmacological intervention to reduce systolic blood pressure in hypertensive patients.]]>
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