<![CDATA[Abstract: Interstitial lung disease (ILD) is a group of lung disorders characterized by chronic inflammation and fibrosis, with a global prevalence ranging from 6.3 to 71 cases per 100,000 population. One subtype, connective tissue disease–associated ILD (CTD-ILD), is closely related to immune system dysregulation and progressive fibrosis. We reported a 45-year-old woman with CTD-ILD prone to malnutrition due to increased metabolic demands and reduced intake caused by dyspnea, nausea, and vomiting. This condition may impair muscle function, reduce lung capacity, and worsen clinical outcomes. Therefore, nutritional assessment plays a crucial role in patient management. Interventions include a balanced diet and nutritional support to meet energy and protein requirements, targeting 1.2–1.5 g/kgBW/day. Supplementation with vitamin D at a dose of 5,000 IU once daily and micronutrients were provided to support metabolism and immune function. During treatment, the patient showed improvement in energy intake, reaching up to 95% of daily requirements and enhanced clinical response through continuous nutrition education. In patients with ILD, especially CTD-ILD, vitamin D plays a supportive therapeutic role by modulating immune responses, reducing fibrotic processes, preserving respiratory muscle function, and supporting bone health. In conclusion, vitamin D deficiency is prevalent in CTD-ILD patients and is linked to disease progression, making vitamin D supplementation an important component of maintenance therapy. Keywords: interstitial lung disease; malnutrition; vitamin D]]>
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