Diana Sunardi
Departemen Ilmu Gizi Fakultas Kedokteran Universitas Indonesia Indonesian Hydration Working Group - FKUI

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Asupan Serat Pangan dan Hubungannya dengan Keluhan Konstipasi pada Kelompok Dewasa Muda di Indonesia Bardosono, Saptawati; Surjadi Handoko, Iwan; Audy Alexander, Ruth; Sunardi, Diana; Devina, Almira
Cermin Dunia Kedokteran Vol 47, No 12 (2020): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (110.26 KB) | DOI: 10.55175/cdk.v47i12.1247

Abstract

Walaupun sampai saat ini konstipasi fungsional masih beragam definisinya, gejalanya sering dikeluhkan karena dirasakan mengganggu kualitas hidup khususnya, pada kelompok dewasa muda, dan bila tidak ditangani dengan baik akan berdampak negatif bagi kesehatan. Asupan serat yang memadai merupakan salah satu alternatif yang efektif untuk mengatasi masalah tersebut, namun asupan sayur dan buah masyarakat di Indonesia masih jauh dari angka kecukupan yang dianjurkan; jumlah asupan serat harian pekerja dewasa muda di Jakarta bervariasi antara 3,3-27,4 g. Tambahan serat pangan dalam diet sehari-hari diharapkan dapat meningkatkan asupan serat sehingga dapat bermanfaat untuk mengatasi keluhan konstipasi.Although until now functional constipation still has various definitions, the symptoms are often interfering with quality of life, especially in young adults. If not managed properly, it may have a serious negative impact on health. Adequate fiber intake is an effective alternative to overcome this problem, but vegetables and fruits intake in Indonesia is still far from adequate. A recent pilot study found that the daily fiber intake among young adult workers in Jakarta is varied between 3.3–27.4 g. Additional dietary fiber in daily diet is expected to increase fiber intake so that it can be useful for dealing with complaints of constipation. 
Correlation between carbohydrate, protein and fat intake with serum c-reactive protein level in lung cancer patients stage IIIB-IV Patricia Amanda; Diana Sunardi; Noorwati Sutandyo
World Nutrition Journal Vol. 1 No. 2 (2018)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V01i2.0006

Abstract

Serum Lactate Dehydrogenase Activity and Its Corellation with Carbohydrate Intake in Advanced Lung Cancer Patients claresta diella; Ninik Mudjihartini; Diana Sunardi; Dian Novita Chandra; Yulhasri Yulhasri; Achmad Mulawarman Jayusman
World Nutrition Journal Vol. 2 No. 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V02.i2.0002

Abstract

Introduction : The aim of this study was to determine serum lactate dehydrogenase activity and its correlation with carbohydrate intake in advanced lung cancer patients at Dharmais National Cancer Hospital Jakarta. Cancer Cells are characterized by increase anaerobic glycolysis termed the Warburg effect with lactate as an end product, catalyzed by LDH enzyme. Activities of lactate in cancer influences on tumor growth initiation, survival, proliferation, angiogenesis and metastasis. Serum LDH activity can be used as a diagnostic, prognostic, and predictive marker for tumor sensitivity and resistancy to therapy.Methods :56 subjects of advanced lung cancer from Dharmais National Cancer Hospital Jakarta were included in this cross sectional study. Subjects were recruited by consecutive sampling. Food intake of total carbohydrate was obtained by utilizing 24 hours food recall method. The activity of  serum LDH (IU/L) was measured by using enzymatic spectrophotometry method on automated analyzer.Results :The mean of age subjects was 56,98 ± 10,36 years old and 55,4% were male. Carbohydrate intake based on 24 hours food recall was 57,64 ± 10,85%. The median of LDH activity was 541,5 (164–6539) IU/L, 60,7% was increase.Conclusion :This study showed medium negative significant correlation (p = 0,017, r = - 0,317) between total carbohydrate intake per day in grams with LDH serum activity. If carbohydrate source is reduced, the LDH enzyme will increase to keep the glycolysis process going. The results of this study indicate that an adequate carbohydrate needed in patients with cancer.
Correlation between Zinc Intake and Zinc Serum Levels with C-reactive Protein Level in Head and Neck Cancer Patients Muningtya Philiyanisa Alam; Diana Sunardi; Ikhwan Rinaldi
World Nutrition Journal Vol. 2 No. 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V02.i2.0003

Abstract

The inflammatory process of head and neck cancer leads to an increase the proinflammatory cytokines and the synthesis of c-reactive protein (CRP), which then causes metabolic alteration and anorexia in the patients. Zinc is one of  nutrient that has an important role in suppressing inflammation, but it is reported that about 65% of head and neck cancer patients have zinc deficiency. The aim of this cross sectional study is to determine the correlation between zinc intake and serum zinc levels with CRP level as an effort in reducing inflammation process in head and neck cancer patients. Subjects were collected by consecutive sampling in the Oncology Polyclinic Rumah Sakit Kanker Dharmais, from 49 subjects 67,3% were men, most subjects were in the age range between 46–65 years. The highest frequency (65,3%) is nasopharyngeal cancer and 69,4% are already in stage IV. All subjects (100%) in this study have a zinc intake below the recommended dietary allowance (RDA) in Indonesia. The mean serum zinc level of the subjects was 9.83±2.62 μmol/L. Most subjects have elevated CRP levels. There was a weak negative correlation between zinc concentration and CRP levels of subjects (r =-0.292, p =0.042), but there was no correlation between zinc intake and CRP levels of subjects (r =-0.25).
Prediction of Post-operative Survival of Colorectal Cancer Patient By Using the Prognostic Nutritional Index: An Evidence-Based Case Report Nurul Ratna Manikam; Yosua Y Kristian; Luana Lidwina; Ayu Diandra Sari; Diana Sunardi
World Nutrition Journal Vol. 2 No. 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V02.i2.0005

Abstract

Background: Colorectal cancer patients may be treated with several modalities and one of them is surgical treatment. Surgery in cancer patients is risky procedure and may not always resulted in prolonged survival. Therefore, before receiving any recommended treatment, the patient’s prognosis has to be assessed and defined properly. Several methods are available to assess the prognosis of cancer patients; one of them is the prognostic nutritional index (PNI).Objective: This study aimed to predict the survival of a colorectal cancer patient post-operatively by calculating the pre-operative PNI score.Method: Literature searching was done using inclusion and exclusion criteria on two databases, i.e. the PubMed and the Cochrane Library. The outcome was survival (disease-free survival, relapse-free survival, or overall survival).Results: Five articles that address the clinical question were retrieved. All indicated that a patient with low PNI score (<44.5) had a shorter overall survival (HR between 1.92 and 3.98 with all p values were <0.05).Conclusion: Pre-operative PNI score can be used to assess the overall survival of a colorectal cancer patient who underwent surgical resection. Patients with a PNI score > 44.5 had better survival than lower PNI score.
Higher Nutritional Status of Lung Cancer Cachexia Patients is Associated with Higher Functional Capacity and Appetite Diana Sunardi; Saptawati Bardosono
World Nutrition Journal Vol. 2 No. 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V02.i2.0006

Abstract

Introduction: Lung cancer is highly prevalent and the major cause of cancer-related deaths worldwide.  Severity of weight loss has been shown to have a negative impact on patients’ performance and quality of life.  Early detection of anorexia and decline of functional capacity will be very usefull to prevent severe weight loss and a better prognosis. Methods: A cross sectional study was conducted in Dharmais Cancer Hospital.  Subjects were lung cancer patients newly diagnosed or a minimal of 2 months pasca chemotherapy or radiotherapy, taken consecutively from inpatients and outpatients.  Results: Subjects eligible for the study were 47, with a composition of 55.3% men and 44.7% women in the age range from 36–79 years old. There were significant relationship between body weight and BMI with ECOG score. Body weight, BMI  and weight loss related significantly with VAS appetite and SNAQ score.  These result indicate that subjects with a higher BMI and a lower weight loss have a better physical performa and appetite.  There were significant relation between haemoglobin level, anemia status and serum albumin level with appetite and risk for anorexia. This result indicate that subjects with normal haemoglobin  and albumin have a good appetite and a lower risk for anorexia.  Conclusions: Positive prognosis of cancer patients can be obtained by maintaining BMI and preventing weight loss, since both affected the already known prognostic marker functional capacity significantly.  Serum Albumin and hemoglobin are not only simple test, but also brings benefits, a clinical marker that may be used to assess the risk of anorexia.
Correlation between hair zinc level and cognitive function in elderly population Dian Sarah Mutiara; Diana Sunardi; Esthika Dewiasty
World Nutrition Journal Vol. 3 No. 2 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i2.0008

Abstract

Introduction: Neurodegenerative disease is the most problem in elderly. Amyloid β (Aβ) accumulation is the major cause of cognitive impairment. Zinc has an important role in antioxidant and Aβ accumulation process. This study aimed to evaluate the correlation between hair zinc level and cognitive function in elderly.Methods: A cross sectional study was conducted involving 58 subjects of elderly in Jakarta. Subjects were recruited by consecutive sampling. Hair zinc level was measured by inductively coupled plasma emission spectrometer (ICPS) and cognitive function assessed by abbreviated mental test (AMT). Data analysis was done by spearman rank correlation test and p-value less than 0.05 were considered statistically significant.Results: The mean of age was 65.4 ± 4.4 years old and 56.9% of subjects were female. The mean of hair zinc level was 123.23 ± 69.71 µg/gram hair and 32.8% subjects had hair zinc deficiency. There was 91.4% subjects had normal cognitive function. The study showed no correlation between hair zinc level and cognitive function in elderly (p=0.871 ; r=-0.022).Conclusions: There was no correlation between hair zinc level and cognitive function in elderly. Further research is expected to be performed with different level of cognitive function.Keywords: cognitive, elderly, hair zinc level, zinc.
Correlation between Serum Hugh Sensitivity C-Reactive Protein With Dietary Intake of Indonesian Lactating Mothers Karin Wiradarma; Diana Sunardi; Ninik Mudjihartini
World Nutrition Journal Vol. 3 No. 1 (2019): Volume 03 Issue 1 Include Supplements Oral Presentation Abstracts of 14th Sympo
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i1.0008

Abstract

Background and Objectives:Chronic low-grade inflammation has emerged as important pathophysiology of non-communicable diseases, which can cause negative effects to mother and baby. Dietary intake has been known as important factor to affect inflammation, which can be measured by high-sensitivity C-reactive protein (hs-CRP). This study aimed to examine the correlation between serum hs-CRP with dietary intake in lactating mothers.Methods:A cross-sectional study was conducted by consecutively enrolling 71 lactating mothers, 3-6 months post-partum, age 20-35 years old, visiting Grogol Petamburan and Cilincing community health center between February and April 2019. Dietary assessment was conducted using semi-quantitative food frequency questionnaire. Anthropometric measurements included were pre-pregnancy weight, post-partum weight, and body height. Serum hs-CRP was measured by immunoturbidimetry method. Spearman correlation was used, with p<0.05 considered significant.Results:Correlation was found between serum hs-CRP and energy (r = 0.372, p = 0.001), carbohydrate (r = 0.295, p = 0.013), and vitamin B6 (r = -0.285, p = 0.016) intake. We also found that serum hs-CRP was correlated with pre-pregnancy (r = 0.296, p = 0.012) and post-partum BMI (r = 0.430, p<0.001).Conclusion:Energy, carbohydrate, and vitamin B6 intakes are positively correlated with serum hs-CRP level.
Correlation between Hair Zinc Level and Cognitive Function in Elderly Dian Sarah Mutiara; Diana Sunardi; Esthika Dewiasty
World Nutrition Journal Vol. 3 No. 1 (2019): Volume 03 Issue 1 Include Supplements Oral Presentation Abstracts of 14th Sympo
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i1.0007

Abstract

Background and Objectives : Neurodegenerative disease is the most problem in elderly. Amyloid β (Aβ) accumulation is the major cause of cognitive impairment. Zinc has an important role in antioxidant and Aβ accumulation process. This study aimed to evaluate the correlation between hair zinc level and cognitive function in elderly.Methods : A cross sectional study was conducted involving 58 subjects of elderly in Jakarta. Subjects were recruited by consecutive sampling. Hair zinc level was measured by inductively coupled plasma emission spectrometer (ICPS) and cognitive function assessed by abbreviated mental test (AMT). Data analysis was done by spearman rank correlation test[DN1]  and p-value less than 0.05 was considered statistically significant.Results : The mean of age was 65.4 ± 4.4 years old and 56.9% of subjects were female. The mean of hair zinc level was 123.23 ± 69.71 µg/gram hair and 32.8% subjects had hair zinc deficiency. There was 91.4% subjects had normal cognitive function. The study showed no correlation between hair zinc level and cognitive function in elderly (p=0.871 ; r=-0.022).Conclusion : There was no correlation between hair zinc level and cognitive function in elderly. Further research is expected to be performed with different level of cognitive function.
Zinc Deficiency Among Lactating Mothers in Jakarta : Associated Factors Dian Araminta Ramadhania; Diana Sunardi; Ali Sungkar
World Nutrition Journal Vol. 3 No. 1 (2019): Volume 03 Issue 1 Include Supplements Oral Presentation Abstracts of 14th Sympo
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i1.0006

Abstract

Background and Objectives : Deficiency of zinc is prevalent worldwide mostly in developing countries. However, its prevalence among vulnerable group such as lactating mothers is still unknown in most populations. This study aimed to determine the prevalence of zinc deficiency among lactating mothers in Jakarta and factors that influence it.Methods :A cross sectional study was conducted in Puskesmas Kecamatan Grogol Petamburan, West Jakarta and Puskesmas Kecamatan Cilincing, North Jakarta between February and April 2019. A total of 75 lactating mothers at 3–6 months postpartum, aged 20–40 years old were recruited using consecutive sampling method. Subjects were interviewed for education levels, occupation, physical activity, types of breastfeeding (exclusive or not), and numbers of parity. Dietary assessment of zinc and protein was carried using semi quantitative food frequency questionnaire (FFQ). Weight and height were measured to assess the body mass index (BMI). Blood samples were taken to analyze serum zinc concentrations. Descriptive analysis, one way ANOVA, and unpaired t-test were used, p-values ≤0.05 were considered significant.Results :The mean of serum zinc was 62.33 ± 11.89 and zinc deficiency was found in 76% of the subjects. There were no significant differences of serum zinc related to education levels, occupation, types of breastfeeding, numbers of parity, zinc intakes, protein intakes, and categories of BMI. Significant difference of serum zinc was found between levels of daily physical activity (p = 0.008) – light, moderate, and vigorous.    Conclusion :Zinc deficiency was prevalent among lactating mothers in Jakarta. There was a significant difference of serum zinc between different levels of daily physical activity.
Co-Authors Achmad Mulawarman Jayusman Adelina Haryono Afifa, Nadhira Nuraini Ali Sungkar Ali Sungkar Almira Devina Anak Agung Eka Widya Saraswati Andayani, Diyah Eka Andry Kelvianto Anin Ika Rosa Ardesy Melizah Kurniati arieska felicia Audy Alexander, Ruth Ayu Diandra Sari Ayu Diandra Sari Badriul Hegar Bernie Endyarni Medise Budi Wiweko Budiati Sutanto, Luciana C Rinaldi A Lesmana Chandra, Dian Novita claresta diella Dadang Makmun Devina, Almira Dewi Friska Dian Araminta Ramadhania Dian Araminta Ramadhania Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Diyah Eka Andayani Diyah Eka Andayani Diyah Eka Andayani Dwi Nastiti Iswarawanti Dwirini Retno Gunarti Dyah Arum Kusumaningtyas E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erfi Prafiantini Ervira Wahyuni Esthika Dewiasty Esthika Dewiasty Esthika Dewiasty Evania Astella Setiawan Evania Astella Setiawan Fadilah Fadilah, Fadilah Fransisca Olivia Gabriella Nurahmani Putri Gloriana Seran Godong, Bernardine Handayani Eka Puspita Sari Hasan Maulahela, Hasan Helda Khusun Ikhwan Rinaldi Iwan Surjadi Handoko Jessica Ferdi Juferdy Kurniawan Karin Wiradarma Khusun, Helda Kirana, Annisa Nurul Krisadelfa Sutanto Krisadelfa Sutanto Luana Lidwina Maggie Nathania Marvin Marino Mauluddy, Anggita Citra Resmi Melyarna Putri Mulianah Daya Muningtya Philiyanisa Alam Neng Tine Kartinah Almuktabar Ninik Mudjihartini Noorwati Sutandyo Novi Silvia Hardiany Nurhayati M Rasyid Nurul Ratna Manikam Nurul Ratna Mutu Manikam Patricia Amanda Pauline Octaviani Prajna Adhityarani Purwantini, Dian Purwita Wijaya Laksmi Putri Novia Choiri Insani Rachmawati, Dessy Suci Rahmita, Kartika Soka Raphael Kosasih Rasyid, Nurhayati M Ratih, Mia Puspita Ratnayani Reisa Melisa Wijaya Rini Sekartini Rizki Yusrini Pohan Rudy Hidayat Ruth Audy Alexander Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Sarah Christy Sepmeitutu, Iwandheny Shabrina, Arifah Sheena R. Angelia Sifa Aulia Wicaksari Stefani, Shiela Steffi Sonia Surjadi Handoko, Iwan Sutanto, Krisadelfa Tarigan, Ananda Putri Tiara Aninditha Titis Prawitasari, Titis Triyanta Yuli Pramana Wella Angelia Wiji Lestari Wiji Lestari Wina Sinaga Wina Sinaga Witjaksono, Firisha Virgidewi Wulandari, Yohannessa Yosua Y Kristian Yosua Yan Kristian Yulhasri Yulhasri Yulianti Wibowo, Yulianti