Jurnal Analis Medika Biosains (JAMBS)
Vol. 13 No. 02 (2026): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)

Meta Analysis Validation for Cadmium (Cd) Determination in Cosmetic Products: A Literature Review

Ni Putu Laksmi Cintyaningrum (Universitas Mataram)
Eskarani Tri Pratiwi (Unknown)



Article Info

Publish Date
26 Sep 2026

Abstract

Cosmetics are widely used daily necessities, with increasing public awareness of personal appearance. These products may be contamined with the heavy metals cadmium (Cd), which poses health risks when concentration exceed established safety limits. Since cosmetics are applied to variuos external parts of the body, from head to the feet, ensuring their safety is essential. This article reviews the validation of cadmium (Cd) analysis methods in cosmetics using various instruments, including Atomic Absorption Spectrometry (AAS), Flame Atomic Absorption Spectrometry (FAAS), Graphite Furnance Atomic Absorption Spectrometry (GFAAS), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES), and Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). The review indicates that the studies generally satisfy validation parameters, as demonstrated by linearity (R2 > 0,99) in ICP-OES dan AAS, accuracy in FAAS wthin acceptance range (80-110%), precision of GFAAS with low relative standard deviation (%RSD ≤ 2%), and most limits of detection (LOD) and limits of quantification (LOQ) for all instruments below the detected cadmium (Cd) concentrations. Several studies reported cadmium (Cd) concentrations exceeding the safe limits of ≤ 5 ppm, as specified by BPOM Regulation No.16. In summary, selecting appropiate analytical instruments and thoroughly validating methods are esssential to ensure the reliability of cadmium analysis and to improve cosmetic product quality.

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Journal Info

Abbrev

home

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions

Description

JAMBS (Jurnal Analis Medika Bio Sains) is a journal that provides a forum for publishing articles related to food analysis, mikrobiology, hematolgy, clinical chemistry, parasitology, immunoserology, histology. Scientific articles dealing with the following topics in food analysis, mikrobiology, ...