The Effect of Alcohol Consumption in Adolescents on Serum Glutamic Oxaloacetic Transaminase (SGOT) And Serum Glutamic Pyruvic Transaminase (SGPT) Levels: Pengaruh Konsumsi Alkohol Pada Remaja Terhadap Kadar Serum Glutamic Oxaloacetic Transaminase (SGOT) Dan Serum Glutamic Pyruvic Transaminase (SGPT)

Navita, Rigi
Aliviameita, Andika

Indonesian Journal Health Science and Medicine
Vol. 3 No. 3 (2026): Desember

General Background: Alcohol consumption is associated with changes in liver function, while Serum Glutamic Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT) are examined as biochemical parameters related to liver function. Specific Background: Adolescents consuming alcohol may have different SGOT and SGPT levels according to the duration of alcohol consumption. Knowledge Gap: The differences in SGOT and SGPT levels between adolescent alcohol consumers with different consumption durations require laboratory-based evaluation. Aims: This study aimed to analyze differences in SGOT and SGPT levels among adolescents consuming alcohol for 1–3 years and more than 3–5 years. Results: This experimental laboratory study used a cross-sectional approach and involved 30 adolescent respondents from the Balongbendo and Tulangan areas who consumed alcohol. SGOT and SGPT examinations were performed using the IFCC UV enzymatic method with a photometer. Independent Samples T-Test analysis showed no significant difference in SGOT levels between the two consumption-duration groups (p=0.087), whereas a significant difference was found in SGPT levels (p=0.000). Novelty: The study specifically compares SGOT and SGPT levels according to alcohol consumption duration among adolescents, demonstrating different statistical findings for the two liver enzymes. Implications: The findings provide laboratory-based information on SGOT and SGPT levels among adolescent alcohol consumers and indicate that SGPT differed significantly between the examined consumption-duration groups. Key Findings Highlights SGOT levels showed no significant difference between the two consumption-duration groups (p=0.087). SGPT levels showed a significant difference between adolescents consuming alcohol for 1–3 years and more than 3–5 years (p=0.000). The study examined 30 adolescent alcohol consumers using the IFCC UV enzymatic method. Keywords : The study examined 30 adolescent alcohol consumers using the IFCC UV enzymatic method.