The Relationship Between Hemoglobin Levels With Erythrocyte Count and Platelet In Patients With DHF (Dengue Hemorrhagic Fever): Hubungan Antara Kadar Hemoglobin Dengan Jumlah Eritrosit dan Trombosit Pada Penderita DBD (Demam Berdarah Dengue)]

Rafilah, Naura Naflah
Aliviameita, Andika

Indonesian Journal Health Science and Medicine
Vol. 3 No. 3 (2026): Desember

Dengue hemorrhagic fever (DHF) is an acute disease associated with hematological changes that require laboratory monitoring, particularly hemoglobin, erythrocyte, and platelet parameters. General Background: Hemoglobin, erythrocyte, and platelet examinations are important in supporting DHF diagnosis and assessing hematological conditions related to plasma leakage and bleeding. Specific Background: Hemoglobin levels may change with hemoconcentration, while thrombocytopenia is commonly observed in DHF; erythrocytes also carry hemoglobin in the circulation. Knowledge Gap: Previous findings reported varying relationships among hematological parameters, while the relationship between hemoglobin levels and erythrocyte and platelet counts in DHF patients at the study setting required further examination. Aims: This study aimed to determine the relationship between hemoglobin levels and erythrocyte and platelet counts in DHF patients. Results: Secondary data from 31 DHF patients at Siti Hajar Islamic Hospital Sidoarjo were analyzed using Spearman's test. The mean hemoglobin level was 13.50 g/dL, the mean erythrocyte count was 4,946,774/µl, and the mean platelet count was 138,129/µl. The analysis showed no significant relationship between hemoglobin and erythrocyte count (p=0.146) and between hemoglobin and platelet count (p=0.796). Novelty: The study provides site-specific evidence that these hematological parameters did not show significant statistical relationships among the examined DHF patients. Implications: These findings support the use of hemoglobin, erythrocyte, and platelet examinations as complementary laboratory parameters in DHF assessment rather than assuming a significant relationship between hemoglobin and either erythrocyte or platelet counts. Key Findings Highlights The mean red-cell measurement remained within the stated reference interval. The mean bleeding-cell measurement was below the stated reference interval. Spearman analysis produced p-values of 0.146 and 0.796 for the two tested associations. Keywords : Dengue Hemorrhagic Fever, Hemoglobin Levels, Erythrocyte Count, Platelet Count, Hematological Parameters