Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Volume 14. No. 3 July 2026

Spontaneous Pregnancy Rates with and without Ovulation Induction after Post-Laparoscopic Neosalpingostomy for Stage III–IV Hydrosalpinx

Indra Adi Susianto (Faculty of Medicine Universitas Catholic Soegijapranata Department of Obstetrics Minimally Invasive Surgery)
Olivia Franciska Laksmana (Faculty of Medicine Universitas Catholic Soegijapranata)
 Hervyasti Purwiandari (Anugerah Women and Children Hospital Department of Obstetrics and Gynecology)
Deni Dwi Ariani (Department of Obstetrics and Gynecology)
Agung Pramartha Irawan (Anugerah Women and Children Hospital)



Article Info

Publish Date
27 Jul 2026

Abstract

Objective: To compare pregnancy outcomes between natural conception and ovulation induction following laparoscopic neosalpingostomy in women with stage III–IV hydrosalpinx. Methods: A quasi-experimental study was conducted between 2014 and 2019 involving 70 infertile women who underwent laparoscopic neosalpingostomy. Participants were assigned to either a natural conception group or an ovulation induction group receiving clomiphene citrate and estradiol valerate. Patients were followed for six to seven months postoperatively. Pregnancy outcomes were analyzed using the chi-square test and multivariate logistic regression, with statistical significance set at p < 0.05. Results: The overall pregnancy rate was 83% within seven months after surgery. Forty-one pregnancies occurred in the natural conception group. No significant association was found between ovulation induction or maternal age >35 years and term pregnancy (p > 0.05). Ectopic pregnancy occurred in 4–5% of cases. Multivariate logistic regression analysis identified no independent predictors of term pregnancy. Conclusion: Laparoscopic neosalpingostomy remains a viable fertility-preserving treatment option for women with advanced hydrosalpinx. Pregnancy outcomes were comparable between women who conceived naturally and those who received ovulation induction therapy. Keywords: hydrosalpinx, laparoscopic neosalpingostomy, pregnancy outcomes, spontaneous pregnancy

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Journal Info

Abbrev

journal

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published ...