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All Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Indra Adi Susianto
Faculty of Medicine Universitas Catholic Soegijapranata Department of Obstetrics Minimally Invasive Surgery
Health Professions Medicine & Pharmacology Public Health

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Spontaneous Pregnancy Rates with and without Ovulation Induction after Post-Laparoscopic Neosalpingostomy for Stage III–IV Hydrosalpinx Indra Adi Susianto; Olivia Franciska Laksmana;  Hervyasti Purwiandari; Deni Dwi Ariani; Agung Pramartha Irawan
Indonesian Journal of Obstetrics and Gynecology Volume 14. No. 3 July 2026
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v14i3.1726

Abstract

Objective: To compare pregnancy outcomes between natural conception and ovulation induction following laparoscopic neosalpingostomy in women with stage III–IV hydrosalpinx. Methods: A quasi-experimental study was conducted between 2014 and 2019 involving 70 infertile women who underwent laparoscopic neosalpingostomy. Participants were assigned to either a natural conception group or an ovulation induction group receiving clomiphene citrate and estradiol valerate. Patients were followed for six to seven months postoperatively. Pregnancy outcomes were analyzed using the chi-square test and multivariate logistic regression, with statistical significance set at p < 0.05. Results: The overall pregnancy rate was 83% within seven months after surgery. Forty-one pregnancies occurred in the natural conception group. No significant association was found between ovulation induction or maternal age >35 years and term pregnancy (p > 0.05). Ectopic pregnancy occurred in 4–5% of cases. Multivariate logistic regression analysis identified no independent predictors of term pregnancy. Conclusion: Laparoscopic neosalpingostomy remains a viable fertility-preserving treatment option for women with advanced hydrosalpinx. Pregnancy outcomes were comparable between women who conceived naturally and those who received ovulation induction therapy. Keywords: hydrosalpinx, laparoscopic neosalpingostomy, pregnancy outcomes, spontaneous pregnancy
Co-Authors Agung Pramartha Irawan Deni Dwi Ariani Olivia Franciska Laksmana  Hervyasti Purwiandari