Background: Chronic kidney disease (CKD) requires complex self-care, and hemodialysis-related symptoms may disrupt sleep quality. Both self-care and sleep quality are important patient-reported outcomes in holistic nursing.Objective: To describe self-care and sleep quality among CKD patients undergoing hemodialysis in a hemodialysis unit in Kendari City, Indonesia. Methods: A descriptive cross-sectional study included 71 adults receiving hemodialysis, selected through purposive sampling. Self-care was assessed using the CKD Self-Care Scale (CKD-SCS), and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Data were analyzed univariately using IBM SPSS Statistics, and frequencies and percentages were reported. Results: The majority of respondents were female (45/71; 63.4%), had a college education (35/71; 49.3%), and were aged 20–25 years (47/71; 66.2%). Good self-care was recorded in 39 participants (54.9%), moderate self-care in 21 (29.6%), and poor self-care in 11 (15.5%). Good sleep quality was recorded in 37 participants (52.1%), moderate in 19 (26.8%), and poor in 15 (21.1%). Conclusion: Most CKD patients undergoing hemodialysis reported good self-care and good sleep quality. However, nearly half of the participants had moderate or poor outcomes in each domain. Orem's Self-Care Deficit Nursing Theory supports individualized assessment of therapeutic self-care demands and rest-related needs. Nursing assessment should address both treatment self-management and sleep-related symptoms.
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