This study aims to analyze the effect of Total Asset Turnover (TATO) and Debt to Equity Ratio (DER) on Return on Assets (ROA) in transportation and logistics companies listed on the Indonesia Stock Exchange for the 2022–2025 period. This study uses a quantitative method with an associative causal approach. The population consisted of seven transportation and logistics companies listed on the Indonesia Stock Exchange, with saturated sampling used to select all companies as the research sample. Secondary data were obtained from annual financial reports and analyzed using multiple linear regression, classical assumption tests, and hypothesis testing with SPSS. The results showed that TATO and DER partially had a significant effect on ROA. Simultaneously, TATO and DER had a significant effect on ROA in transportation and logistics companies during the 2022–2025 period
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