<![CDATA[Abstract: The pharmaceutical and herbal industry in Indonesia has continued to develop, creating opportunities and increasing competition among firms. This study aims to examine the effects of Growth Opportunity and profitability on firm value at PT Industri Jamu dan Farmasi Sido Muncul Tbk during 2016–2025. A quantitative associative research design was employed. The population comprised of the company's annual financial reports, with ten annual reports selected as the sample using purposive sampling. Secondary data were collected through documentation, literature review, and internet searching. Growth Opportunity was measured using Asset Growth, profitability using Return on Assets (ROA), and firm value using Price to Book Value (PBV). The data were analyzed using IBM SPSS Statistics 26 through descriptive statistics, classical assumption tests, multiple linear regression, coefficient of determination, F-test, and t-test. The results show that Growth Opportunity and profitability simultaneously affect firm value (F = 8.309; p = 0.014). Partially, Growth Opportunity significantly affects firm value (β = 0.213; p = 0.034), while profitability also has a significant effect (β = 0.291; p = 0.005). The study concludes that both factors are significant determinants of firm value.]]>
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