<![CDATA[Infectious disease transmission in healthcare settings remains a critical challenge that threatens both patient and healthcare worker safety. Strengthening nurses’ knowledge and attitudes through structured training programs is essential to improve infection prevention practices and compliance with personal protective equipment (PPE) use. This study aimed to analyze the effectiveness of classical training methods and classical training combined with educational booklets in improving nurses’ knowledge and attitudes regarding infectious disease transmission and PPE use. A quasi-experimental design with a pretest–posttest comparison group approach was conducted among 72 nurses, divided equally into two intervention groups (n = 36 each). Data were analyzed using Wilcoxon and Mann-Whitney. The results showed that in the classical training group, the mean knowledge score increased from 23.17 ± 1.134 to 23.89 ± 0.319 (p = 0.001), and the mean attitude score increased from 66.83 ± 4.365 to 69.50 ± 4.226 (p = 0.005). In the classical training combined with booklet group, the mean knowledge score increased from 23.33 ± 0.894 to 23.86 ± 0.424 (p = 0.006), while the mean attitude score increased from 66.81 ± 3.463 to 68.08 ± 4.607 (p = 0.026). However, there were no statistically significant differences in knowledge improvement (p = 0.496) or attitude improvement (p = 0.263) between the two groups. In conclusion, both training methods were effective in significantly improving nurses’ knowledge and attitudes regarding infectious disease transmission and PPE use. Nevertheless, no significant difference in effectiveness was found between the classical training method and the classical training combined with educational booklets. Keyword: Knowledge, attitude, training methods, infectious diseases, personal protective equipment]]>
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