The advancement of artificial intelligence (AI) is transforming educational practices and requiring teachers to continuously develop their professional competencies to meet 21st-century demands. This article aims to analyze the roles, integration strategies, opportunities, and challenges associated with AI in enhancing teachers' professional competence. The study employs a qualitative method using a literature review approach. Data were gathered from scholarly journal articles, books, educational regulations, and various academic sources relevant to AI, teacher professionalism, and 21st-century learning. A descriptive-analytical approach was used to identify, compare, and synthesize findings from the selected sources. The study reveals that AI can assist teachers in lesson planning, developing instructional materials and media, conducting lessons, designing assessments, and providing feedback. Conversely, AI integration faces challenges regarding digital literacy, information accuracy, technological dependency, data security, and ethical usage. Integrating AI requires accompanying measures such as training, mentoring, information verification, and the reinforcement of teachers' professional responsibility.
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