Biomedika
Vol 18, No 2 (2026): Biomedika August 2026

RISK FACTORS OF QTC INTERVAL PROLONGATION IN HEMODIALYSIS PATIENTS

Hendra Wana Nur'amin (Universitas Lambung Mangkurat, Banjarmasin)
Djallalludin (Universitas Lambung Mangkurat, Banjarmasin)
Andhita Apriliana (Universitas Lambung Mangkurat, Banjarmasin)
Farhanaqilah Mazaya (Universitas Lambung Mangkurat, Banjarmasin)
Hijratun Nisa (Universitas Lambung Mangkurat, Banjarmasin)



Article Info

Publish Date
08 Oct 2026

Abstract

QTc interval prolongation is an important risk factor for fatal arrhythmias and sudden cardiac death. Identifying factors associated with QTc prolongation may help prevent cardiovascular complications. This study aimed to analyze clinical factors associated with the risk of QTc prolongation in hemodialysis patients. This study was conducted with a cross-sectional approach. Bivariate logistic regression analysis was performed to analyze the association of sex, age, body mass index (BMI), and comorbidities (diabetes mellitus, hypertension, heart failure, pneumonia, anemia, and hyperkalemia) with QTc prolongation. 189 subjects were enrolled and divided into two groups based on QTc duration ≥500 ms ( n =41) and <500 ms ( n =148). Of all variables, gender showed a significant association with QTc prolongation (p=0.02; prevalence odds ratio (POR)=2.40; 95% CI: 1.15-4.99), with women having a higher risk of QTc interval ≥500 ms than men. Risk factors such as age >60 years, BMI, diabetes mellitus, hypertension, heart failure, pneumonia, anemia, and hyperkalemia did not show a significant association (p>0.05). These findings support the need for routine ECG monitoring, especially in female patients, to prevent arrhythmias and cardiovascular mortality.

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Journal Info

Abbrev

biomedika

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Biomedika is one of the efforts of the Faculty of Medicine of University Muhammadiyah Surakarta to improve the academic atmosphere, as a publication of research results from lecturers and students. The existence of Biomedika is expected to enhance the activity and quality of research in medical and ...