Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Vol. 32 No. 3 (2026)

ACQUIRED HEMOPHILIA A IN AN ELDERLY FEMALE: A CASE REPORT

Sri Suryo Adiyanti (Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta)
Fidrianie Ramadhona (Faculty of Medicine, Universitas Indonesia, Jakarta)



Article Info

Publish Date
27 Jul 2026

Abstract

Acquired hemophilia A (AHA) is a blood clotting disorder caused by the formation of specific autoantibodies that can inhibit the action of Factor VIII (FVIII). This case presents a 65-year-old female with a 4-month history of bleeding manifestation, including left subconjunctival hemorrhage, bruising on the right arm, and swelling in the left arm and right knee. Laboratory examination revealed an isolated prolonged activated partial thromboplastin time (aPTT), FVIII activity <1%, and inhibitor FVIII titer 206.4 Bethesda units (BU), with therapeutic management based on hemostatic control with intravenous Eloctate® (rFVIIIFc) and immunosuppressive therapy. The underlying condition associated with the development of AHA was not found in this patient.

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Journal Info

Abbrev

patologi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

Description

Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) is a journal published by “Association of Clinical Pathologist” professional association. This journal displays articles in the Clinical Pathology and Medical Laboratory scope. Clinical Pathology has a couple of ...