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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Fidrianie Ramadhona
Faculty of Medicine, Universitas Indonesia, Jakarta
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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ACQUIRED HEMOPHILIA A IN AN ELDERLY FEMALE: A CASE REPORT Sri Suryo Adiyanti; Fidrianie Ramadhona
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 32 No. 3 (2026)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v32i3.2596

Abstract

Acquired hemophilia A (AHA) is a blood clotting disorder caused by the formation of specific autoantibodies that can inhibit the action of Factor VIII (FVIII). This case presents a 65-year-old female with a 4-month history of bleeding manifestation, including left subconjunctival hemorrhage, bruising on the right arm, and swelling in the left arm and right knee. Laboratory examination revealed an isolated prolonged activated partial thromboplastin time (aPTT), FVIII activity <1%, and inhibitor FVIII titer 206.4 Bethesda units (BU), with therapeutic management based on hemostatic control with intravenous Eloctate® (rFVIIIFc) and immunosuppressive therapy. The underlying condition associated with the development of AHA was not found in this patient.
Co-Authors SRI SURYO ADIYANTI