<![CDATA[Introduction: Empathy is an important part in patient-doctor relationship. Empathy should be taught early in dental education for better patients care in the future. Empathy learning carried out through patient simulation in pre-clinical stage and interaction with real patient in clinical stage. The aim of this research was to find out the difference of empathy level between pre-clinical and clinical dental students in Dental Faculty of Yarsi University. Case Study: This is a descriptive analytical study with cross-sectional design, conducting for all active students in pre-clinical and clinical stage. Every students filled out questionnaire from The Jefferson’s Scale of Physician Empathy Medical Students (JSPE-S) which has been modified. Discussion: The study results showed that empathy level of pre-clinical stage dental students were higher than clinical stage dental students with significant p value 0.038 (p<0.05). It was also discovered that the empathy level of dental students were affected by academic level, stress level, dental task burden and social-culture factors. Conclusion: Empathy learning should be integrated in pre-clinical and clinical stage of dental education curriculum.]]>
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