ABSTRACTIrritant Contact Dermatitis (ICD) is one of the most common occupational skin diseases among nail art workers due to frequent and direct contact with chemical irritants such as acetone, ethyl acetate, methacrylic acid, isopropyl alcohol, toluene, and quaternary ammonium compounds. This study aims to evaluate a case of ICD in a nail art worker and to explore its association with occupational exposure. The research was conducted using a case study method, applying the seven-step approach to diagnosing occupational diseases, which includes medical history, physical examination, and a review of relevant literature. A 28-year-old woman who had been working in a nail art salon for three years presented with painful sensations on the fingertips of both hands, accompanied by dryness, cracking skin, and mild itching—especially after contact with acetone-based nail polish remover. Based on clinical evaluation, occupational history, and supporting scientific references, the patient was diagnosed with ICD as an occupational disease. Repeated exposure to acetone was found to have a strong association with the onset of symptoms. The diagnosis also considered the duration of employment, length of exposure per session, infrequent use of personal protective equipment (PPE), and the absence of relevant non-occupational risk factors. This study concludes that the ICD in this patient is an occupational disease. Education and the consistent use of PPE are essential for preventing and controlling recurrence Keywords: Irritant Contact Dermatitis, Nail Art Workers, Occupational Diagnosis, Acetone
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