This study aims to develop entrepreneurship-based science LKPD on environmental pollution. The development uses a modified 4-D model consisting of three stages: define, design, and develop. The results of the needs analysis show that learning at MTs Nurussalam Besito is still conventional, theoretical, and does not integrate practical activities or projects. The designed worksheets contain material on environmental pollution, entrepreneurship, and waste utilization projects. The validation results show that the worksheets are in the highly feasible category, with a material expert score of 95.83%, media expert score of 92.50%, and science teacher score of 91.67%. A trial involving 20 students produced a very positive response with a percentage of 85.25%. Thus, the developed LKPD is considered feasible, interesting, and able to help students understand the concept of environmental pollution contextually and foster an entrepreneurial attitude
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