Journal Pharmasci (Journal of Pharmacy and Science)
Vol. 7 No. 1 (2022): Journal Pharmasci (Journal of Pharmacy and Science)

Antibacterial Sensitivity Test of Generic Ceftriaxone Injection Against Salmonella typhi: Uji Sensitivitas Antibakteri Sediaan Injeksi Ceftriaxone Generik terhadap Salmonella typhi

Emma Susanti (Sekolah Tinggi Ilmu Farmasi Riau)
Leony Liza Andriani (Sekolah Tinggi Ilmu Farmasi Riau)
Musyrina Rahmah (Sekolah Tinggi Ilmu Farmasi Riau)



Article Info

Publish Date
27 Jan 2022

Abstract

Research on antibacterial sensitivity test of several generic ceftriaxone injection preparations against Salmonella typhi have been conducted. The purpose of this study was to determine the antibacterial sensitivity of several generic ceftriaxone injection preparations against Salmonella typhi using the Agar diffusion method, with 3 samples taken from 3 different manufacturers in hospital S Pekanbaru. The result of inhibition zone diameter obtained by product P is 27,76 mm, product Q is 28,83 mm, and the product R is 29,96 mm. Positive control and negative control used ceftriaxone disc 30 µg the inhibition zone diameter was obtained 18,1 mm and the disc paper was dripped with sterile aquadest. This is because the amount of ceftriaxone injection test substance in the disk is greater than the positive control ceftriaxone level. In the test sample there are 1000 µg/disc while the positive control had 30 µg/disc, it means that the number of Ceftriaxone test substances was 33,3 time greater than the positive control. The test results show that ceftriaxone injection has an inhibitory power with a strong category based on the Clinical Laboratory Standards Institute (2017), and positive control using ceftriaxone 30 µg disc showed moderate inhibition.

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Journal Info

Abbrev

jps

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Journal of Pharmacy and Science (Pharmasci) publishes full-length original articles and reviews. The scope of the journal is pharmaceutical and basic science, including its research and application. The editors, therefore, welcome contributions on the following topics: 1. Clinical pharmacy 2. ...