Journal Pharmasci (Journal of Pharmacy and Science)
Vol. 10 No. 1 (2025): Journal Pharmasci (Journal of Pharmacy and Science)

Hydroxyapatite From Kepah Shells (Polymesoda erosa) and Its In Vitro Sunscreen Activity: Hidroksiapatit Dari Cangkang Kerang Kepah (Polymesoda erosa) dan Aktivitas Tabir Surya Secara In Vitro

Pri Iswati Utami (Muhammadiyah University Purwokerto)
Wiranti Sri Rahayu (Muhammadiyah University Purwokerto)
Karina Festia Ramadani (Unknown)
Astrit Mayang Sari (Muhammadiyah University Purwokerto)



Article Info

Publish Date
09 Jan 2025

Abstract

Sunscreen innovation from natural ingredients is needed, because there are many advantages obtained from the use of these natural ingredients, such as the absence of side effects, and easy to obtain. Kepah shells (Polymesoda erosa) are found in Cilacap, Central Java. Kepah shells containing calcium carbonate can be used in the manufacture of hydroxyapatite (HAP). Hydroxyapatite can be used as a sunscreen agent that can effectively absorb the ultraviolet light. Hydroxyapatite was isolated from kepah shells (Polymesoda erosa). The analysis of HAP is done using Fourier Trasform Infra Red (FTIR) spectroscopy to find out functional groups. The sun protection factor (SPF) value of HAP was determined using the spectrophotometric UV-Vis method. FTIR spectra of HAP showed the presence of a hydroxyl group at 3039-3749 cm-1, a phosphate group at 520-621 cm-1 and a carbonate group at 1489-2156 cm-1. HAP from kepah shells has sunscreen potential with minimal protection at a concentration of 200 ppm; and ultra protection at a concentration of 1000 ppm. The average SPF result of HAP 1000 ppm clam shells is 19.23 (ultra protection) and at a concentration of 200 ppm is 0.59 (minimum protection). HAP from kepah shells has the potential to be developed as a sunscreen ingredient. The development of sun protection products still requires further research.

Copyrights © 2025






Journal Info

Abbrev

jps

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Journal of Pharmacy and Science (Pharmasci) publishes full-length original articles and reviews. The scope of the journal is pharmaceutical and basic science, including its research and application. The editors, therefore, welcome contributions on the following topics: 1. Clinical pharmacy 2. ...