Chemistry learning in the 21st century requires innovative and interactive learning media to increase students' engagement. The needs analysis at SMAN 10 Padang and SMAN 17 Padang showed that the using of technology-based learning media was not yet optimal, while Thermochemistry contains abstract concepts requiring visualization. This study aimed develop valid PowerPoint-iSpring Suite 11 learning media assisted by Zep Quiz for Thermochemistry material for Grade XI senior high school students. This study employed educational design research (EDR) use the Plomp development model through the preliminary research and prototyping phase, resulting in Prototype I, II, and III. The research was limited to Prototype III through expert review and one-to-one evaluation. Validation was conducted by three Chemistry Education lecturers from the Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, using questionnaires covering content and construct aspects. Data were analyzed using Aiken's V index, with V ≥ 0.92 indicating validity. The content and construct validation results obtained Aiken's V value of 0.92 for each indicator, categorized as valid. The one-to-one evaluation involving three students showed that the media was attractive, easy to understand, provided clear instructions, and helped students understand Thermochemistry. Thus, the developed learning media met the validity criteria.
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