Mosquitoes are insects that can disturb human activities and contribute to the spread of various diseases. One way to reduce the risk of mosquito bites is to use repellents. Lemongrass leaves (Cymbopogon citratus (DC.) Stapf) contain bioactive compounds and essential oils that have the potential to be developed as natural mosquito repellents. This study aimed to identify the bioactive compounds and analyze the mosquito repellent activity of lemongrass leaves based on previous research. The method used was a Systematic Literature Review (SLR), with articles searched through Google Scholar, PubMed, ScienceDirect, the Directory of Open Access Journals (DOAJ), and Garuda. The reviewed articles were limited to publications from 2021 to 2026 and selected based on their relevance to the research topic. The initial review of eight articles indicated that lemongrass leaf extracts exhibited repellent activity against several mosquito species under specific testing conditions. One study reported a repellency rate of 89.5% at a concentration of 25%, while another found that cream and emulgel formulations containing 2% extract provided more than 80% repellency. Lemongrass essential oil also showed potential for development into aromatherapy candles as mosquito repellent products. Its effectiveness was influenced by extract concentration, solvent type, formulation, and mosquito species tested. In conclusion, lemongrass leaves have potential as a natural mosquito repellent; however, further research on their effectiveness, safety, and duration of protection is still needed.
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