Healthcare accessibility remains a critical determinant of quality of life (QoL), particularly among vulnerable populations in developing nations like Indonesia. Despite national universal health coverage initiatives, systemic disparities persist across socioeconomic lines and geographic regions. This study investigates the relationship between healthcare accessibility and the quality of life among vulnerable populations in Indonesia, focusing on geographical barriers, financial constraints, and utilization rates. Utilizing a quantitative cross-sectional design, this study analyzes secondary data from recent national socioeconomic and health surveys. Multivariate regression analysis was conducted to evaluate how physical distance, out-of-pocket health expenditure, and health insurance ownership impact physical, psychological, social, and environmental dimensions of QoL among low-income households and elderly populations. The findings indicate that financial barriers—specifically out-of-pocket costs and limited insurance coverage—significantly diminish overall QoL, with psychological and environmental domains being the most severely affected. Furthermore, rural-urban disparities in geographic accessibility exacerbate health inequalities, restricting timely medical interventions for marginalized groups. Targeted policy interventions are urgently required to reduce out-of-pocket financial burdens, expand primary healthcare infrastructure in remote areas, and streamline healthcare delivery for vulnerable groups in Indonesia to foster equitable health outcomes and improve overall well-being.
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