<![CDATA[Background: Patients receiving maintenance hemodialysis frequently experience impaired health-related quality of life (HRQoL). Theory-driven self-management education delivered through digital technology may support adaptive responses to chronic illness. Objective: To examine the effect of Roy Adaptation Model (RAM)–based self-management education delivered through an Android application on HRQoL among patients undergoing hemodialysis. Methods: This study used a two-group randomized pretest–posttest design at the K.R.M.T. Wongsonegoro Hospital hemodialysis unit in Semarang, Indonesia. The study population is 163 patients in the dialysis population, 115 eligible participants were enrolled and allocated to an intervention group (n=58) or control group (n=57) using a computer-generated random sequence in Microsoft Excel. The intervention consisted of five 20–30-minute education sessions delivered through an Android application during the first three weeks, with follow-up monitoring through week 4 and post-intervention assessment during week 5. The control group received routine hospital education. HRQoL was assessed using the Indonesian KDQOL-36. Within-group changes were examined using the Wilcoxon signed-rank test and between-group differences in change scores using the Mann–Whitney U test. Results: Total KDQOL-36 scores increased significantly in both groups (p0.001). The median total score increased from 51.5 (IQR 47–56) to 81 (IQR 78–84) in the intervention group and from 51 (IQR 46.5–56) to 71 (IQR 66–76) in the control group. The between-group comparison of change scores was statistically significant (p0.001). Conclusion: RAM-based self-management education provided through the Android app improves the quality of life of hemodialysis patients.]]>
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