Jaringan Laboratorium Medis
Vol 8 No 2 (2026): November 2026

Antibiotic Susceptibility Profile of Methicillin-Resistant Staphylococcus aureus (MRSA) Isolates from Diabetic Foot Wounds

Yasmin Husnul Khotimah (Poltekkes Kemenkes Bandung)
Oos Fatimah Rosyati (Poltekkes Kemenkes Bandung)
Hafizah Ilmi Sufa (Poltekkes Kemenkes Bandung)
Ira Gustira Rahayu (Poltekkes Kemenkes Bandung)



Article Info

Publish Date
01 Oct 2026

Abstract

Diabetic foot wound infection is a complication of diabetes mellitus that can be caused by various bacteria, including Methicillin-Resistant Staphylococcus aureus (MRSA), which may complicate the selection of antibiotic therapy because of its high level of resistance. This study aimed to identify MRSA isolates and determine their antibiotic susceptibility profiles from diabetic foot wounds of patients with diabetes mellitus at RUMAT Diabetes Wound Care, Bandung City. This descriptive laboratory experimental study used 30 diabetic foot wound samples collected from patients with diabetes mellitus. The isolates were identified by culture on Blood Plate Agar and Mannitol Salt Agar, followed by Gram staining, catalase test, coagulase test, and MRSA screening using cefoxitin discs. Antibiotic susceptibility testing was performed using the Kirby–Bauer disk diffusion method on Mueller–Hinton Agar according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. The results showed that 7 (23.3%) isolates were identified as MRSA. All MRSA isolates were obtained from patients with type 2 diabetes mellitus who had been diagnosed with diabetes for at least one year. The MRSA isolates exhibited 100% susceptibility to azithromycin and amikacin; 85.7% susceptibility to tetracycline, gentamicin, ciprofloxacin, levofloxacin, and trimethoprim-sulfamethoxazole; 71.4% susceptibility to amoxicillin, erythromycin, and clindamycin; and 57.1% susceptibility to chloramphenicol. These antibiotic susceptibility profiles may provide useful information to support the selection of antibiotic therapy for diabetic foot wound infections in Bandung City.

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Journal Info

Abbrev

JLM

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Public Health

Description

Jurnal Online Jaringan Laboratorium Medis adalah peer-reviewed journal yang mempublikasikan artikel-artikel ilmiah tentang ilmu kesehatan yang meliputi bidang Analis Kesehatan yang meliputi Penelitian Bakteriologi, Kimia Klinik, Parasitologi, Toksikologi Klinik, Hematologi, Sitohistoteknologi dan ...