Human resources play a vital role in determining an organization's success, which is reflected in employee performance. At Karya Husada Hospital, employee performance has not yet reached an optimal level, which is presumed to be associated with employee engagement and self-efficacy. Therefore, this study aims to examine the effects of employee engagement and self-efficacy on employee performance, both partially and simultaneously. This study employed a quantitative method with descriptive and verificative approaches. The population consisted of 183 permanent employees of Karya Husada Hospital, all of whom were selected as respondents using a saturated sampling technique. Data were collected through a Likert-scale questionnaire and analyzed using validity and reliability tests, classical assumption tests, multiple linear regression analysis, the coefficient of determination (R²), the t-test, and the F-test with the assistance of the Statistical Package for the Social Sciences (SPSS). The results indicate that employee engagement has a positive and significant effect on employee performance (t = 6.622; p < 0.001). Likewise, self-efficacy has a positive and significant effect on employee performance (t = 4.949; p < 0.001). Simultaneously, employee engagement and self-efficacy significantly influence employee performance (F = 47.932; p < 0.001), with a coefficient of determination (R²) of 0.348. These findings suggest that improving employee engagement and self-efficacy can enhance employee performance and may serve as a reference for Karya Husada Hospital in developing more effective human resource management strategies.
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