<![CDATA[Smoking remains a common habit among workers facing high stress and heavy workloads, including mining company drivers. Toxic compounds and radical species in cigarette smoke can disrupt oxidative balance and damage hepatocytes. These changes can be reflected in the activity levels of the enzymes Serum Glutamic Pyruvic Transaminase (SGPT) and Serum Glutamic Oxaloacetic Transaminase (SGOT). This study aimed to assess SGPT and SGOT levels in active smokers working as mining company drivers in the Loa Janan Ilir area. It was a descriptive study with a cross-sectional design, involving a total of 45 respondents selected via purposive sampling. SGPT and SGOT levels were measured using the kinetic method in accordance with IFCC standards, and the data were analyzed descriptively. SGPT values fell within the reference range for 41 participants (91.1%), while 4 participants (8.9%) showed values exceeding the limit. Regarding SGOT, 31 participants (68.9%) were within the reference range, and 14 participants (31.1%) had values above the limit. Thus, the activity of both enzymes in the majority of participants remained within the reference range, although elevated SGOT levels were observed in a number of participants.]]>
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