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All Journal Borneo Journal of Medical Laboratory Technology Health Care : Jurnal Kesehatan Jurnal Ilmiah Kesehatan Masyarakat Sains Medisina Health Research Journal of Indonesia
Sresta Azahra
Poltekkes Kemenkes Kalimantan Timur
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Evaluasi Kadar Kreatinin dan Mikroalbumin dengan HbA1C Suryanata Kesuma; Sresta Azahra; Amalia Diah Suci Rahmah
Borneo Journal of Medical Laboratory Technology Vol. 5 No. 2 (2023): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v5i2.4790

Abstract

Diabetes Mellitus (DM) is a metabolic disease caused by high blood glucose levels (hyperglycemia). Hyperglycemia is caused due to lack of insulin secretion in the body. Glycemic control in diabetic patients is seen in HbA1C levels. One of the complications of DM is diabetic nephropathy. Renal function abnormalities associated with diabetic nephropathy are indicated by increased levels of creatinine and microalbumin. This shows that it is necessary to monitor kidney function in DM. Monitoring DM patients with HbA1C levels <6.5% is desirable, with these levels indicating that glycemic control is good. This study aimed to determine the relationship between creatinine and microalbumin levels with HbA1C <6.5% in Diabetes Mellitus patients in Samarinda. This type of research is analytic with a cross-sectional design. Spearman correlation statistical test. The sample of this study was 107 DM patients with HbA1C levels <6.5% who did medical checkups at the Media Farma Clinic, Samarinda. Sampling is done by Total Sampling. HbA1C examination method with turbidimetry. Method of checking creatinine by Jaffe reaction. Method of examination of microalbumin with immunoturbidimetry. All parameters are quality controlled before measurement. The measurement results were validated by a clinical pathologist. The results showed that the correlation of creatinine with HbA1C <6.5% obtained p value = (0.826), microalbumin with HbA1C <6.5% obtained p value = (0.146), and creatinine with microalbumin obtained p value = (0.082). All these results indicate that H0 is accepted and Ha is rejected. This study concludes no significant relationship exists between creatinine and microalbumin values with HbA1C levels <6.5% in Diabetes Mellitus in Samarinda, especially Media Farma Clinic.
Profil Bakteri Patogen dan Antibiotik pada Gangren Diabetes Melitus di RSUD Abdul Wahab Sjahranie Samarinda Desi Wahyuni; Suryanata Kesuma; Sresta Azahra
HEALTH CARE: JURNAL KESEHATAN Vol 12 No 1 (2023): Health Care : Jurnal Kesehatan
Publisher : STIKes Payung Negeri Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36763/healthcare.v12i1.370

Abstract

Diabetes Mellitus can be triggered by environmental factors and unhealthy lifestyles such as overeating, fat, lack of activity, and stress. Diabetes Mellitus can also appear due to hereditary factors. Diabetes Mellitus can cause various complications including gangrenous wounds. To determine the appropriate use of antibiotics, appropriate treatment, and the spread of antibiotic resistance does not occur in patients with gangrene with Diabetes Mellitus, it is necessary to identify the appropriate bacterial species. The study aimed to identify the bacterial species found in wound infections in diabetic with gangrenous complications at AWS Hospital. This type of research is descriptive with exploratory design. The research sample was pus (pus) with gangrene in inpatient diabetic in November - December at AWS Hospital. A total of 29 samples were found in pus gangrenous DM wound infection, there were 11 species of gram-negative and gram-positive pathogenic bacteria. Antibiotic sensitivity test on the Staphylococcus epidermidis bacterial species was more resistant to antibiotics by 81%, the Proteus mirabilis bacterial species was more Intermediate against antibiotics by 65%, and the Proteus hauseri bacterial species was more sensitive to bacteria by 66%. The most infecting pathogenic bacteria are gram-negative bacteria with the species Proteus mirabilis and the most resistant and sensitive antibiotics are Ceftizoxime, gentamicin, and Piperacillin/Tazobactam.
Uji Cemaran dan Identifikasi Bakteri Staphylococcus aureus pada Bumbu Giling di Pasar Tradisional Kota Samarinda Aisyah Mutia Iskandar; Supri Hartini; Sresta Azahra; Tiara Dini Harlita
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 5 No. 3 (2026): Juli 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v5i3.8720

Abstract

Ground spice paste is a widely consumed food product sold in traditional markets with varying environmental conditions. Differences between wet and dry stalls may affect environmental sanitation and the microbiological safety of the product, including contamination by Staphylococcus aureus. This study aimed to determine the Total Plate Count (TPC) and identify S. aureus in cooked ground spice pastes sold in traditional markets in Samarinda City. A descriptive observational study was conducted using 12 samples consisting of rendang, soup, and rawon spice pastes collected from wet and dry stalls. TPC was determined using the pour plate method on Plate Count Agar (PCA), while S. aureus was identified using Mannitol Salt Agar (MSA) followed by biochemical tests. Environmental sanitation conditions were assessed through direct observation, and the data were analyzed descriptively. The results showed that all samples met acceptable organoleptic criteria; however, several samples exceeded the maximum TPC limit established by SNI 7388:2009 and were contaminated with S. aureus. Samples exceeding the maximum TPC limit were more frequent in wet stalls (83.3%) than in dry stalls (66.7%), with the highest count found in rendang spice paste. Meanwhile, S. aureus was detected more frequently in wet stalls (50.0%) than in dry stalls (33.3%). The higher descriptive proportions of microbiological contamination in wet stalls coincided with poorer sanitation conditions, including standing water, high humidity, and open storage. These findings indicate that cooked ground spice pastes sold in traditional markets are susceptible to microbiological contamination, particularly in stalls with inadequate sanitation.
Hubungan Lama Menderita Diabetes Mellitus Tipe 2 terhadap Pertumbuhan Mikroba sebagai Faktor Predisposisi Infeksi Rongga Mulut Sresta Azahra; Tiara Dini Harlita; Deanita Rabiatul Zhadiah Puspitasari; Hutami Putri Pase
Health Research Journal of Indonesia Vol 4 No 4 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i4.1090

Abstract

Pendahuluan: Diabetes mellitus (DM) adalah penyakit metabolik. Kadar glukosa saliva pada penderita DM yang meningkat dapat menjadi faktor predisposisi terhadap pertumbuhan mikroba (bakteri dan jamur) yang dapat menyebabkan infeksi rongga mulut. Tujuan: Mengetahui hubungan lama menderita DM tipe 2 terhadap pertumbuhan mikroba sebagai faktor predisposisi infeksi rongga mulut. Metode: Metode penelitian yaitu observasional analitik dan desain cross sectional. Populasi berjumlah 57 penderita DM tipe 2 Puskesmas Harapan Baru, Samarinda dan 33 saliva yang diambil dengan teknik purposive sampling. Identifikasi bakteri dengan media Blood Agar Plate (BAP), pewarnaan Gram, serta uji biokimia. Identifikasi jamur dilakukan menggunakan media Sabouraud Dextrose Agar (SDA), chromagar, pewarnaan LPCB, dan uji germ tube. Data dianalisis secara univariat dan bivariat. Hasil: Penelitian ini didapatkan hasil pertumbuhan positif jamur Candida sp. pada 29 responden (87,8 %) dan pertumbuhan positif bakteri Gram positif pada 30 responden (90,9%). Hasil positif pertumbuhan mikroba pada pasien DM  yang menderita ≥3 tahun sebanyak 24 responden (72,7%). Hasil uji statistik didapatkan hasil nilai p= 0,036 (<0,05), artinya terdapat hubungan bermakna signifikan lama menderita DM dengan pertumbuhan mikroba. Simpulan: Terdapat hubungan bermakna signifikan lama menderita DM tipe 2 dengan pertumbuhan mikroba sebagai faktor predisposisi infeksi rongga mulut.
Potensi Kombinasi Ekstrak Keji Beling dan Binahong Sebagai Antibakteri Terhadap Bakteri Gram Negatif Penyebab Ulkus Diabetikum TIARA DINI HARLITA; GANEA QORRY AINA; SRESTA AZAHRA
Sains Medisina Vol 4 No 2 (2025): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v4i2.844

Abstract

Ulkus diabetikum adalah satu keluhan yang terjadi pada pasien diabetes melitus yang sulit disembuhkan dan dapat menyebabkan infeksi bakteri hingga gangren diabetik. Penggunaan antibiotik jangka waktu lama dan dosis yang tidak sesuai dapat menimbulkan ketahanan bakteri yang berdampak pada meningkatkan biaya pengobatan dan angka kematian. Oleh karena itu, penggunaan tanaman obat sebagai alternatif untuk pengobatan mulai banyak dimanfaatkan karena lebih aman dalam penggunaan jangka waktu lama seperti pada tanaman binahong dan keji beling berpotensi sebagai antibakteri karena memiliki kandungan senyawa aktif. Penelitian ini bertujuan untuk menguji potensi senyawa yang diperoleh dari ekstrak etanol tanaman keji beling dan bihanong sebagai antibakteri terhadap bakteri Gram negatif penyebab ulkus diabetikum. Penelitian ini menggunakan metode eksperimental dengan Rancangan Acak Lengkap. Uji antibakteri dilakukan dengan metode difusi Kirby Bauer terhadap Proteus sp. dan Escherichia coli, kemudian data dianalisis dengan uji ANOVA. Berdasarkan hasil yang didapatkan, baik ekstrak tunggal maupun kombinasi keji beling dan binahong dengan perbandingan 2:1 pada konsentrasi 100 mg/mL memberikan daya hambat terbesar terhadap kedua bakteri. Analisis statistik menunjukkan variasi konsentrasi dan kombinasi berpengaruh nyata (p<0,05). Disimpulkan bahwa kombinasi kedua ekstrak memiliki aktivitas antibakteri alami dan berpotensi sebagai agen pendukung penghambatan bakteri penyebab ulkus diabetikum.
Co-Authors Aisyah Mutia Iskandar Amalia Diah Suci Rahmah Deanita Rabiatul Zhadiah Puspitasari DESI WAHYUNI Ganea Qorry Aina Hutami Putri Pase Kesuma, Suryanata Supri Hartini Tiara Dini Harlita Tiara Dini Harlita