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All Journal Borneo Journal of Medical Laboratory Technology Health Care : Jurnal Kesehatan
Sresta Azahra
Poltekkes Kemenkes Kalimantan Timur
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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Evaluasi Kadar Kreatinin dan Mikroalbumin dengan HbA1C Suryanata Kesuma; Sresta Azahra; Amalia Diah Suci Rahmah
Borneo Journal of Medical Laboratory Technology Vol. 5 No. 2 (2023): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v5i2.4790

Abstract

Diabetes Mellitus (DM) is a metabolic disease caused by high blood glucose levels (hyperglycemia). Hyperglycemia is caused due to lack of insulin secretion in the body. Glycemic control in diabetic patients is seen in HbA1C levels. One of the complications of DM is diabetic nephropathy. Renal function abnormalities associated with diabetic nephropathy are indicated by increased levels of creatinine and microalbumin. This shows that it is necessary to monitor kidney function in DM. Monitoring DM patients with HbA1C levels <6.5% is desirable, with these levels indicating that glycemic control is good. This study aimed to determine the relationship between creatinine and microalbumin levels with HbA1C <6.5% in Diabetes Mellitus patients in Samarinda. This type of research is analytic with a cross-sectional design. Spearman correlation statistical test. The sample of this study was 107 DM patients with HbA1C levels <6.5% who did medical checkups at the Media Farma Clinic, Samarinda. Sampling is done by Total Sampling. HbA1C examination method with turbidimetry. Method of checking creatinine by Jaffe reaction. Method of examination of microalbumin with immunoturbidimetry. All parameters are quality controlled before measurement. The measurement results were validated by a clinical pathologist. The results showed that the correlation of creatinine with HbA1C <6.5% obtained p value = (0.826), microalbumin with HbA1C <6.5% obtained p value = (0.146), and creatinine with microalbumin obtained p value = (0.082). All these results indicate that H0 is accepted and Ha is rejected. This study concludes no significant relationship exists between creatinine and microalbumin values with HbA1C levels <6.5% in Diabetes Mellitus in Samarinda, especially Media Farma Clinic.
Profil Bakteri Patogen dan Antibiotik pada Gangren Diabetes Melitus di RSUD Abdul Wahab Sjahranie Samarinda Desi Wahyuni; Suryanata Kesuma; Sresta Azahra
HEALTH CARE: JURNAL KESEHATAN Vol 12 No 1 (2023): Health Care : Jurnal Kesehatan
Publisher : STIKes Payung Negeri Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36763/healthcare.v12i1.370

Abstract

Diabetes Mellitus can be triggered by environmental factors and unhealthy lifestyles such as overeating, fat, lack of activity, and stress. Diabetes Mellitus can also appear due to hereditary factors. Diabetes Mellitus can cause various complications including gangrenous wounds. To determine the appropriate use of antibiotics, appropriate treatment, and the spread of antibiotic resistance does not occur in patients with gangrene with Diabetes Mellitus, it is necessary to identify the appropriate bacterial species. The study aimed to identify the bacterial species found in wound infections in diabetic with gangrenous complications at AWS Hospital. This type of research is descriptive with exploratory design. The research sample was pus (pus) with gangrene in inpatient diabetic in November - December at AWS Hospital. A total of 29 samples were found in pus gangrenous DM wound infection, there were 11 species of gram-negative and gram-positive pathogenic bacteria. Antibiotic sensitivity test on the Staphylococcus epidermidis bacterial species was more resistant to antibiotics by 81%, the Proteus mirabilis bacterial species was more Intermediate against antibiotics by 65%, and the Proteus hauseri bacterial species was more sensitive to bacteria by 66%. The most infecting pathogenic bacteria are gram-negative bacteria with the species Proteus mirabilis and the most resistant and sensitive antibiotics are Ceftizoxime, gentamicin, and Piperacillin/Tazobactam.
Co-Authors Amalia Diah Suci Rahmah DESI WAHYUNI Kesuma, Suryanata