<![CDATA[This research is motivated by the increasingly fierce competition in the vaccine industry and the need for PT Bio Farma (Persero) to maintain and strengthen the competitiveness of its vaccine business. The study aims to analyze the internal and external environments and formulate strategies to strengthen the competitiveness of PT Bio Farma (Persero)'s vaccine business. The study used a qualitative method with a descriptive approach. The research instruments included researchers, interview and observation guides, and documentation. While data analysis was carried out through data collection, reduction, presentation, and verification, followed by IFE, EFE, IE, SWOT, and Porter's Generic Strategies analysis. The results showed that the IE matrix placed the company in quadrant V or hold and maintain with market penetration and product development strategies, while the SWOT matrix generated 12 alternative strategies. The conclusion of the study showed that the differentiation strategy had the highest level of suitability and was the main strategy because it was supported by quality, international standards, R&D, innovation, technology, reputation, service, and distribution.]]>
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